Description

3-Bromo-5-(Trifluoromethyl)Toluene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and trifluoromethyl substituents on a toluene backbone, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic motifs for bioactivity or as a handle for further functionalization via cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorine-containing aromatic cores in electronic materials, contributing to desired dielectric anisotropy and emission properties.
• Polymer Chemistry: Employed to introduce bromine functional groups into polymer chains for further modification or to create monomers for specialty polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3-Bromo-5-(Trifluoromethyl)Toluene
CAS No.	86845-28-5
Molecular Formula	C8H6BrF3
Molecular Weight	239.04 g/mol
Synonyms	1-Bromo-3-methyl-5-(trifluoromethyl)benzene; 3-Methyl-5-(trifluoromethyl)bromobenzene; 3-Bromo-α,α,α-trifluoro-m-xylene; m-Bromo-α,α,α-trifluoro-m-xylene; 5-Bromo-1-methyl-3-(trifluoromethyl)benzene; 3-Bromo-5-(trifluoromethyl)methylbenzene; Toluene, 3-bromo-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(Trifluoromethyl)Toluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.6 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.