Description

4-Methyl-3-(trifluoromethyl)bromobenzene is a high-purity, multi-functional aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring both bromine and trifluoromethyl substituents, makes it a versatile intermediate for introducing specific functionalities into target molecules. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical sectors seeking to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring trifluoromethylated aromatic cores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in cross-coupling reactions and organometallic catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers where fluorine substitution modifies electronic and physical properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Heck, and Buchwald-Hartwig amination reactions to construct complex biaryl systems.
• Fluorine Chemistry Building Block: Integral for introducing the pharmacologically beneficial trifluoromethyl group into diverse molecular scaffolds during drug discovery.

Basic Information

Product Name	4-Methyl-3-(Trifluoromethyl)Bromobenzene
CAS No.	86845-27-4
Molecular Formula	C8H6BrF3
Molecular Weight	239.04 g/mol
Synonyms	1-Bromo-4-methyl-3-(trifluoromethyl)benzene; 3-Trifluoromethyl-4-bromotoluene; 4-Bromo-2-methylbenzotrifluoride; 2-Methyl-α,α,α-trifluoro-4-bromotoluene; 4-Methyl-3-(trifluoromethyl)phenyl bromide; 3-(Trifluoromethyl)-4-bromotoluene; Toluene, 4-bromo-2-methyl-α,α,α-trifluoro-
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-(trifluoromethyl)bromobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.