Description

(-)-Cisapride is a high-purity, single-enantiomer pharmaceutical active ingredient. This compound is a selective serotonin 5-HT4 receptor agonist, primarily valued for its prokinetic properties in gastrointestinal motility research and development. It is essential for pharmaceutical manufacturers and research institutions focused on developing treatments for gastroesophageal reflux disease (GERD) and related motility disorders. Our supply ensures the stringent quality and consistency required for advanced pharmaceutical applications.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of prescription gastrointestinal medications.
• Clinical Research: Used in preclinical and clinical studies investigating therapies for gastroparesis, chronic constipation, and functional dyspepsia.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical labs.
• Mechanistic Studies: Employed in pharmacological research to study serotonin receptor pathways and gastrointestinal physiology.
• Formulation Development: Used in the development of various dosage forms, including tablets and oral suspensions.

Basic Information

Product Name	(-)-Cisapride
CAS No.	86719-31-5
Molecular Formula	C23H29ClFN3O4
Molecular Weight	465.95 g/mol
Synonyms	Cisapride; (3R,4R)-4-Amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide; (-)-(R,R)-Cisapride; R 51619; Prepulsid; Unipride; Alimix; Acenalin; Prizma
EINECS	Contact for details

Quality Control

Our (-)-Cisapride is manufactured under strict quality management systems. Each batch is tested to meet high-purity standards suitable for pharmaceutical research and development, with comprehensive analysis including chiral purity, assay, and impurity profiling. A Certificate of Analysis (COA) detailing specifications and test results is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Chiral Purity (Enantiomeric Excess)	≥99.0%
Related Substances (HPLC)	Total impurities ≤1.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.