Description

Prostaglandin E2 Methyl Oxime is a chemically modified analog of the bioactive lipid mediator Prostaglandin E2 (PGE2). This compound is valued for its enhanced stability compared to the parent molecule, making it a crucial research tool and intermediate in pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences and pharmaceutical industries for biochemical studies, drug discovery, and the synthesis of more complex prostaglandin derivatives.

Application

• Biochemical Research: Used as a stable analog to study the role of PGE2 in inflammation, pain, fever, and reproductive processes.
• Pharmaceutical Intermediates: Serves as a key synthetic building block for the development of novel prostaglandin-based therapeutics.
• Cell Signaling Studies: Employed in vitro and in vivo to investigate EP receptor binding and downstream signaling pathways.
• Reference Standard: Used as a high-purity analytical standard in HPLC and LC-MS for quantification and method validation.
• Drug Discovery Screening: A valuable compound in high-throughput screening assays to identify new modulators of the prostaglandin pathway.

Basic Information

Product Name	Prostaglandin E2 Methyl Oxime
CAS No.	86659-90-7
Molecular Formula	C21H33NO6
Molecular Weight	395.49 g/mol
Synonyms	PGE2 Methyl Oxime; (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid Methyl Oxime; 9-Oxo-11α,15S-dihydroxyprosta-5Z,13E-dien-1-oic Acid Methyl Oxime; Dinoprostone Methyl Oxime; Prostaglandin E2 (PGE2) Methyl Oxime; PGE2-MO; 11-Deoxy-15-hydroxy-9-oxoprostanoic Acid Methyl Oxime Derivative
EINECS	Contact for details

Quality Control

Our Prostaglandin E2 Methyl Oxime is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-grade research and development specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.