Description

2,4-Dichloro-5-Fluorotoluene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its role as a key intermediate for the production of complex, high-value molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for manufacturers and R&D chemists developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty dyes or pigments.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, including antibacterial and antiviral agents.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides where the fluorotoluene moiety enhances biological activity.
• Material Science: Serves as a building block for liquid crystals and advanced polymers with specific optical or electronic properties.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions to introduce the difluoro-chloromethylbenzene structure into more complex molecules.
• Dye & Pigment Manufacturing: Acts as an intermediate for synthesizing specialized fluorinated colorants.
• Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science.

Basic Information

Product Name	2,4-Dichloro-5-Fluorotoluene
CAS No.	86522-86-3
Molecular Formula	C7H5Cl2F
Molecular Weight	179.02 g/mol
Synonyms	1,3-Dichloro-2-fluoro-4-methylbenzene; 2-Fluoro-1,3-dichloro-4-methylbenzene; 5-Fluoro-2,4-dichlorotoluene; 4-Methyl-2,4-dichlorofluorobenzene; 2,4-Dichloro-5-fluoromethylbenzene; Toluene, 2,4-dichloro-5-fluoro-; 86522-86-3 (CAS)
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-Fluorotoluene is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting specifications for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical properties is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.