Description

n-Iodosaccharin (CAS NO 86340-94-5) is a specialized halogenated saccharin derivative, serving as a versatile and highly reactive iodinating agent in advanced organic synthesis. Its core value lies in enabling precise electrophilic iodination reactions, which are critical for introducing iodine atoms into complex molecular frameworks. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for building novel compounds.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the electrophilic iodination of active pharmaceutical ingredients (APIs) and advanced intermediates, particularly in the development of thyroid hormone analogs and radio-imaging agents.
• Agrochemical Research: Used in the synthesis of novel halogenated pesticides and herbicides, where the iodine moiety can enhance biological activity and environmental persistence.
• Material Science: Employed in the preparation of iodine-functionalized polymers and organic electronic materials for optoelectronic applications.
• Organic Synthesis Reagent: A valuable tool in academic and industrial R&D labs for regioselective iodination of heterocycles, aromatics, and other sensitive substrates under mild conditions.
• Chemical Biology Probes: Facilitates the synthesis of iodinated probes and tags used in bio-conjugation and imaging studies.

Basic Information

Product Name	n-Iodosaccharin
CAS No.	86340-94-5
Molecular Formula	C7H4INO3S
Molecular Weight	309.08 g/mol
Synonyms	1-Iodosaccharin; Saccharin, N-iodo derivative; N-Iodosaccharin; 2-Iodobenzoic sulfimide; 3-Oxo-2,3-dihydro-1,2-benzisothiazole 1-iodide; 1,2-Benzisothiazol-3(2H)-one, 1-iodo-; Iodosaccharin; 1,2-Benzisothiazolin-3-one, 1-iodo-
EINECS	Contact for details

Quality Control

Our n-Iodosaccharin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity, and is supplied with a comprehensive Certificate of Analysis (COA). We adhere to relevant industry standards for fine chemicals, and custom purity grades or analytical packages are available to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.