Description

Pre-Calcitriol Ptad Adduct is a high-purity, specialized chemical derivative used as a critical intermediate in advanced pharmaceutical synthesis. This compound is essential for researchers and manufacturers developing and scaling up production of vitamin D analogs and related therapeutic agents. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical sectors for process development, analytical reference standards, and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of calcitriol (1,25-dihydroxyvitamin D3) and its structural analogs.
• Process Chemistry: Used in research and development for route scouting and optimization of vitamin D-related drug manufacturing processes.
• Analytical Standard: Serves as a certified reference material (CRM) for quality control and method validation in HPLC and LC-MS analysis.
• Biochemical Research: Employed in studies investigating the metabolism, receptor binding, and biological activity of vitamin D compounds.
• Fine Chemical Synthesis: Intermediate for creating novel steroidal and secosteroidal compounds with potential therapeutic applications.
• GMP Manufacturing: Suitable for use in cGMP environments for the production of clinical trial materials and commercial APIs.

Basic Information

Product Name	Pre-Calcitriol Ptad Adduct
CAS No.	86307-44-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1α,25-Dihydroxycholecalciferol Precursor Adduct; PTAD Derivative of Pre-Calcitriol; Vitamin D3 Intermediate PTAD Adduct; 1α,25-Dihydroxyvitamin D3 Synthesis Intermediate; (5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3-diol Derivative; Pre-1,25-(OH)2D3 PTAD Adduct; Cyclohexadiene Adduct of Pre-Calcitriol
EINECS	Contact for details

Quality Control

Our Pre-Calcitriol Ptad Adduct is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.