Description

2-Fluoro-5-(Trifluoromethoxy)Toluen CAS NO 86256-57-7 is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its unique trifluoromethoxy and fluorine substituents, which are critical for modulating the lipophilicity, metabolic stability, and electronic properties of target molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and electro-optical materials due to its electron-withdrawing characteristics.
• Advanced Polymer Chemistry: Acts as a monomer or modifier for creating specialty polymers with enhanced chemical resistance and specific optical properties.
• Chemical Research & Development: A versatile building block in academic and industrial labs for exploring new reactions and creating complex molecular architectures.

Basic Information

Item	Detail
Product Name	2-Fluoro-5-(Trifluoromethoxy)Toluen
CAS No.	86256-57-7
Molecular Formula	C8H6F4O
Molecular Weight	194.13 g/mol
Synonyms	1-Fluoro-2-methyl-4-(trifluoromethoxy)benzene; 2-Methyl-1-fluoro-4-(trifluoromethoxy)benzene; 2-Fluoro-5-(trifluoromethoxy)toluene; α,α,α-Trifluoro-2-fluoro-5-methylanisole; 2-Fluoro-α,α,α-trifluoro-5-methylanisole; 4-(Trifluoromethoxy)-2-fluorotoluene; 2-Fluoro-5-(trifluoromethoxy)methylbenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-(Trifluoromethoxy)Toluen is produced under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications to guarantee high purity and batch-to-batch consistency, which is critical for your synthetic processes. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.