Description

2-Chloro-4-Fluorobenzenesulfonyl Chloride is a versatile and highly reactive organosulfur compound that serves as a critical building block in advanced chemical synthesis. Its value lies in its dual functionality, acting as a key sulfonylation reagent and a precursor for more complex sulfonamide derivatives. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with sulfonyl functional groups.
• Material Science: Employed in the creation of specialty polymers, dyes, and liquid crystals where the sulfonyl chloride moiety is incorporated.
• Chemical Research: Serves as a versatile reagent in organic synthesis laboratories for introducing the 2-chloro-4-fluorophenylsulfonyl group into target molecules.
• Custom Synthesis: A fundamental starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	2-Chloro-4-Fluorobenzenesulfonyl Chloride
CAS No.	85958-57-2
Molecular Formula	C6H3Cl2FO2S
Molecular Weight	229.05 g/mol
Synonyms	2-Chloro-4-fluorobenzene-1-sulfonyl chloride; 1-Chloro-2-fluoro-4-(chlorosulfonyl)benzene; 4-Fluoro-2-chlorobenzenesulfonyl chloride; 2-Chloro-4-fluorophenylsulfonyl chloride; Benzenesulfonyl chloride, 2-chloro-4-fluoro-; 2-Chloro-4-fluorobenzene sulfonyl chloride; 2-Chloro-4-fluoro-1-sulfonyl chloride benzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluorobenzenesulfonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.