Description

8-Chloronaphthalene-2-Sulfonyl Chloride is a versatile and highly reactive organic intermediate, primarily valued for its dual functional groups which enable its use as a key building block in sophisticated chemical synthesis. This compound is essential for researchers and manufacturers requiring precise molecular architecture, particularly in the development of active pharmaceutical ingredients and advanced materials. It is a critical raw material for industries focused on pharmaceuticals, agrochemicals, and specialty dyes, where its specific chlorosulfonyl and chloro-substituted naphthalene structure facilitates targeted derivatization.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging its reactive sites to create compounds with specific biological activity.
• Dyestuff and Pigment Manufacturing: Acts as a key intermediate for synthesizing high-performance, light-fast azo and anthraquinone dyes.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers due to its rigid naphthalene backbone.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules in proteomics and diagnostic assay development.
• Cross-Coupling Reactions: Functions as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating complex biaryl structures.

Basic Information

Product Name	8-Chloronaphthalene-2-Sulfonyl Chloride
CAS No.	85915-71-5
Molecular Formula	C10H6Cl2O2S
Molecular Weight	277.12 g/mol
Synonyms	2-Chloro-8-naphthalenesulfonyl chloride; 8-Chloro-2-naphthalenesulfonyl chloride; 2-Naphthalenesulfonyl chloride, 8-chloro-; 1-Chloro-7-naphthalenesulfonyl chloride; NSC 406915; 8-Chloronaphthalene-2-sulphonyl chloride; 8-Chloro-2-naphthylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 8-Chloronaphthalene-2-Sulfonyl Chloride is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of fine chemical and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.