Description

4-Formylbenzenesulfonyl Chloride is a versatile and highly reactive aromatic sulfonyl chloride derivative, serving as a critical bifunctional building block in advanced organic synthesis. Its dual functionality, featuring both an electrophilic sulfonyl chloride group and an aldehyde moiety, makes it indispensable for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with sulfonylurea or sulfonamide backbones.
• Polymer Chemistry: Monomer for producing specialty polymers and resins, such as polyelectrolytes or functionalized materials with aldehyde handles.
• Dye and Pigment Manufacturing: Intermediate in the production of sulfonated dyes and optical brighteners.
• Crosslinking Agent: Used in the modification of proteins, peptides, and other biomolecules via reactions with amine groups.
• Chemical Research & Development: Valuable reagent for parallel synthesis, combinatorial chemistry, and library development in medicinal chemistry.

Basic Information

Product Name	4-Formylbenzenesulfonyl Chloride
CAS No.	85822-16-8
Molecular Formula	C7H5ClO3S
Molecular Weight	204.63 g/mol
Synonyms	4-Formylbenzenesulfonyl chloride; p-Formylbenzenesulfonyl chloride; 4-Carboxybenzenesulfonyl chloride (precursor-related); Terephthalaldehydesulfonyl chloride; Benzaldehyde-4-sulfonyl chloride; p-Aldehydebenzenesulfonyl chloride; 4-(Chlorosulfonyl)benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Formylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent hydrolysis. Keep away from strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0 - 103.0%
Melting Point	92 - 96 °C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.