Description

n-Acetyl-9-Deoxy-9-Fluoroneuraminic Acid is a fluorinated derivative of sialic acid, a critical carbohydrate moiety in glycobiology. This compound serves as a valuable biochemical tool and a key synthetic intermediate for the development of neuraminidase inhibitors and other bioactive molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for applications in antiviral drug discovery, glycoconjugate synthesis, and enzyme mechanism studies.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies of neuraminidases (sialidases) to investigate viral infection mechanisms and host-pathogen interactions.
• Pharmaceutical Intermediates: A key building block in the synthesis of novel antiviral agents, particularly for influenza and other viruses that utilize sialic acid receptors.
• Glycobiology & Glycochemistry: Essential for the chemical and enzymatic synthesis of complex oligosaccharides, glycoproteins, and glycolipids to study cell signaling and recognition.
• Diagnostic Development: Employed in the design and production of diagnostic assays and probes for detecting viral enzymes or specific carbohydrate-binding proteins.
• Enzyme Inhibitor Design: Acts as a core structure for developing transition-state analog inhibitors targeting sialidase enzymes in therapeutic applications.

Basic Information

Product Name	n-Acetyl-9-Deoxy-9-Fluoroneuraminic Acid
CAS No.	85819-28-9
Molecular Formula	C11H18FNO8
Molecular Weight	311.26 g/mol
Synonyms	9-Deoxy-9-fluoro-N-acetylneuraminic acid; 9-Fluoro-9-deoxy-N-acetylneuraminic acid; 5-Acetamido-9-fluoro-3,5,9-trideoxy-D-glycero-D-galacto-non-2-ulosonic acid; 9-F-Neu5Ac; Fluoroneuraminic acid derivative; Sialic acid fluorinated analog; Neu5Ac9F; Inhibitor intermediate
EINECS	Contact for details

Quality Control

Our n-Acetyl-9-Deoxy-9-Fluoroneuraminic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.