Description

K-252C is a potent and selective protein kinase inhibitor belonging to the indolocarbazole alkaloid family. This high-purity biochemical is critical for advanced life science research, particularly in the study of intracellular signaling pathways and cellular regulation. It is an essential tool compound for pharmaceutical R&D, academic institutions, and biotechnology companies focused on oncology, neuroscience, and signal transduction research.

Application

• Biochemical Research: A key inhibitor for studying protein kinase C (PKC) and other serine/threonine kinases in cell signaling cascades.
• Pharmaceutical Development: Used as a reference standard and pharmacological tool in drug discovery programs targeting kinase-related diseases.
• Cell Biology Studies: Employed to investigate the role of specific kinases in processes like cell proliferation, differentiation, and apoptosis.
• Neuroscience Research: Applied in studies exploring kinase function in neuronal survival, synaptic plasticity, and neurodegenerative conditions.
• Oncology Research: Utilized to probe kinase pathways involved in cancer cell growth and survival for potential therapeutic targeting.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	K-252C
CAS No.	85753-43-1
Molecular Formula	C₂₆H₂₁N₃O₅
Molecular Weight	455.46 g/mol
Synonyms	9-Hydroxy-4-methyl-1-oxo-1H,5H,10H-[1,4]oxazino[4,3-a]pyrrolo[3,4-c]carbazole-3,6,10(4H)-trione; Staurosporine analog; Microbial alkaloid K-252c; Antibiotic K 252c; 4'-Demethylamino-4'-hydroxystaurosporine; SF 2370
EINECS	Contact for details

Quality Control

Our K-252C is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant standards for research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to moisture and light. For long-term storage, consider desiccant and under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.