Description

Arphamenine A CAS NO 85713-14-0 is a potent and specific inhibitor of aminopeptidase B, belonging to the class of arphamenines. This compound is a critical biochemical tool for researchers investigating the role of specific aminopeptidases in cellular processes, including protein metabolism, antigen presentation, and signal peptide processing. It is essential for pharmaceutical R&D, academic research, and biotechnology applications focused on enzyme inhibition, mechanism of action studies, and high-throughput screening.

Application

• Biochemical Research: Used as a selective inhibitor to study the function and mechanism of aminopeptidase B in in vitro and cell-based assays.
• Pharmaceutical Development: Serves as a lead compound or reference standard in drug discovery programs targeting aminopeptidase-related diseases.
• Enzymology Studies: Employed to characterize enzyme kinetics, substrate specificity, and inhibition profiles of peptidases.
• Cell Biology & Immunology: Aids in research on antigen processing and presentation pathways within immune cells.
• Proteomics & Protein Chemistry: Utilized to control proteolytic degradation in protein purification and analysis workflows.
• High-Throughput Screening (HTS): Acts as a control or reference inhibitor in screening assays for novel therapeutic agents.

Basic Information

Product Name	Arphamenine A
CAS No.	85713-14-0
Molecular Formula	C15H21N3O4
Molecular Weight	307.35 g/mol
Synonyms	Arphamenine A; NSC 329680; (2S)-2-Amino-5-[[(2S)-2-amino-5-phenylpentanoyl]amino]pentanoic acid; Bestatin analogue; Aminopeptidase B Inhibitor I; Arphamenin A
EINECS	Contact for details

Quality Control

Our Arphamenine A is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific biological activity assays. A detailed Certificate of Analysis (COA) is provided, ensuring traceability and compliance with research-grade standards. We support custom synthesis and purification to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C. Allow the product to equilibrate to room temperature before opening to minimize moisture uptake. Store away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Biological Activity (IC50)	Reported per batch

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.