Description

(4R,5Z,7E,12S,14Z)-4,12-Bis(Acetyloxy)-9-Oxoprosta-5,7,10,14-Tetren-1-Oic Acid Methyl Ester is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound matters for its precise stereochemistry and functional groups, which are critical for studying and modulating biological pathways related to inflammation, smooth muscle contraction, and cellular signaling. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on developing novel therapeutics and conducting detailed pharmacological studies.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex prostaglandin-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe compound for investigating prostaglandin receptors, signal transduction pathways, and enzyme interactions.
• Drug Discovery: Serves as a core scaffold for medicinal chemistry programs aimed at developing new anti-inflammatory, cardiovascular, or ophthalmic drugs.
• Academic Studies: Employed in university and institutional labs for fundamental research in lipid mediator biology and synthetic organic chemistry methodologies.
• Process Development: Utilized in scaling up and optimizing synthetic routes for prostaglandin production under cGMP conditions.

Basic Information

Product Name	(4R,5Z,7E,12S,14Z)-4,12-Bis(Acetyloxy)-9-Oxoprosta-5,7,10,14-Tetren-1-Oic Acid Methyl Ester
CAS No.	85700-42-1
Molecular Formula	C25H32O7
Molecular Weight	444.52 g/mol
Synonyms	Methyl (4R,5Z,7E,12S,14Z)-4,12-Diacetoxy-9-oxoprosta-5,7,10,14-tetraenoate; 9-Oxo-4,12-diacetoxyprosta-5,7,10,14-tetraenoic Acid Methyl Ester; Prostaglandin A2 Methyl Ester Diacetate; PGA2 Methyl Ester Diacetate; (4R,5Z,7E,12S,14Z)-4,12-Diacetoxy-9-oxoprosta-5,7,10,14-tetraenoic Acid Methyl Ester; 4,12-Di-O-acetyl-9-oxo-PGA2 Methyl Ester
EINECS	Contact for details

Quality Control

Our (4R,5Z,7E,12S,14Z)-4,12-Bis(Acetyloxy)-9-Oxoprosta-5,7,10,14-Tetren-1-Oic Acid Methyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS). Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Solubility	Soluble in DMSO, Ethanol, Acetone

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.