Description

4-Bromo-2-Fluorobenzyl Chloride is a versatile halogenated benzyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, where the reactive benzyl chloride group and the halogen substituents enable precise molecular construction for complex targets. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors, particularly for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules containing fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the halogenated benzyl moiety imparts specific biological activity.
• Liquid Crystal & OLED Material Production: Serves as a building block for fluorinated organic electronic materials and liquid crystal compounds.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Polymer Monomer: Incorporated into polymer backbones to modify physical properties like thermal stability and refractive index.
• Organic Synthesis Reagent: Utilized in nucleophilic substitution reactions to introduce the 4-bromo-2-fluorobenzyl group into various molecular frameworks.

Basic Information

Product Name	4-Bromo-2-Fluorobenzyl Chloride
CAS No.	85510-82-3
Molecular Formula	C7H5BrClF
Molecular Weight	223.47 g/mol
Synonyms	1-(Chloromethyl)-4-bromo-2-fluorobenzene; 2-Fluoro-4-bromobenzyl chloride; (4-Bromo-2-fluorophenyl)methyl chloride; α-Chloro-4-bromo-2-fluorotoluene; 4-Bromo-2-fluoro-α-chlorotoluene; 4-Bromo-2-fluorobenzylchloride; Benzene, 1-(chloromethyl)-4-bromo-2-fluoro-
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorobenzyl Chloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Due to its reactivity as an acid chloride derivative, it is recommended to store under an inert atmosphere for long-term stability. Typical storage temperature is 2-8°C for optimal shelf life.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.