Description

Gemeprost is a synthetic prostaglandin E1 (PGE1) analog, a high-purity active pharmaceutical ingredient (API) with significant pharmacological activity. This compound is valued for its potent uterotonic and cervical ripening properties, making it a critical component in specialized pharmaceutical formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of gynecological and obstetric medications, as well as in advanced biochemical research.

Application

• Pharmaceutical API: Primary active ingredient in medications for cervical priming and induction of labor.
• Gynecological Therapeutics: Used in formulations for the medical management of pregnancy termination and postpartum hemorrhage.
• Clinical Research: Serves as a key reference standard and investigational compound in reproductive health and prostaglandin pathway studies.
• Biochemical Synthesis: Intermediate in the synthesis of more complex prostaglandin analogs and related bioactive molecules.
• Veterinary Medicine: Potential application in animal reproductive health management.

Basic Information

Product Name	Gemeprost
CAS No.	85505-25-5
Molecular Formula	C23H38O5
Molecular Weight	394.55 g/mol
Synonyms	ONO 802; 16,16-Dimethyl-trans-δ²-PGE₁ methyl ester; Gemeprostum; 11,15-Dihydroxy-16,16-dimethyl-9-oxoprosta-2,13-dien-1-oic acid methyl ester; 16,16-Dimethyl-trans-δ²-prostaglandin E₁ methyl ester; PGE₁ analog ONO-802; U-46785; Cervagem (brand name component)
EINECS	Contact for details

Quality Control

Our Gemeprost is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling to meet stringent pharmaceutical-grade standards. A Certificate of Analysis (COA) detailing specific results for purity (typically ≥98% by HPLC), related substances, residual solvents, and other critical parameters is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at controlled room temperature (15-25°C) or under refrigeration (2-8°C) as specified. The product is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen) after opening. Keep the container in a dry, cool, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.