Description

Ethanone, 2-Fluoro-1-(3-Hydroxy-4-Methoxyphenyl)- (9Ci) CAS NO 85465-61-8 is a specialized fluorinated aromatic ketone derivative, serving as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in fine chemical synthesis. Its molecular structure, featuring both fluorine and methoxy substituents, makes it invaluable for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily sought by pharmaceutical R&D and custom synthesis organizations for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atom enhances bioavailability and stability.
• Material Science: Serves as a monomer or precursor for specialty polymers and liquid crystals, contributing to advanced material properties.
• Organic Synthesis: A versatile reagent for Friedel-Crafts acylation and other reactions to introduce the 2-fluoro-1-(3-hydroxy-4-methoxyphenyl)ethanone moiety into complex molecules.
• Fluorine Chemistry Studies: Used in academic and industrial research to study the effects of fluorine substitution on aromatic ketone reactivity and electronic properties.

Basic Information

Product Name	Ethanone, 2-Fluoro-1-(3-Hydroxy-4-Methoxyphenyl)- (9Ci)
CAS No.	85465-61-8
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	2'-Fluoro-3'-hydroxy-4'-methoxyacetophenone; 1-(3-Hydroxy-4-methoxyphenyl)-2-fluoroethanone; 2-Fluoro-1-(3-hydroxy-4-methoxyphenyl)ethan-1-one; 3'-Hydroxy-4'-methoxy-2'-fluoroacetophenone; 2-Fluoro-3-hydroxy-4-methoxyacetophenone; 2-Fluoro-1-(4-methoxy-3-hydroxyphenyl)ethanone
EINECS	Contact for details

Quality Control

Our production of Ethanone, 2-Fluoro-1-(3-Hydroxy-4-Methoxyphenyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and production use. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for pharmaceutical intermediates, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.