Description

3-(Difluoromethyl)-2,6-Difluoro-Pyridine is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its unique difluoromethyl and difluoro substitution pattern makes it a valuable intermediate for introducing fluorine atoms into target molecules, enhancing their metabolic stability, lipophilicity, and bioavailability. This compound is primarily sought by R&D and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized fluorinated ligands used in catalysis and material science.
• Functional Material Research: Employed in the synthesis of fluorinated organic electronic materials, such as those used in OLEDs and semiconductors.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-(Difluoromethyl)-2,6-Difluoro-Pyridine
CAS No.	85396-63-0
Molecular Formula	C6H3F4N
Molecular Weight	165.09 g/mol
Synonyms	2,6-Difluoro-3-(difluoromethyl)pyridine; 3-(Difluoromethyl)-2,6-difluoropyridine; Pyridine, 3-(difluoromethyl)-2,6-difluoro-; 85396-63-0; 2,6-Difluoro-3-difluoromethylpyridine
EINECS	Contact for details

Quality Control

Every batch of 3-(Difluoromethyl)-2,6-Difluoro-Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and scale-up. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. For long-term storage, maintaining the container at a controlled room temperature (15-25°C) under an inert atmosphere is recommended to ensure stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.