Description

3-Bromo-4-(Trifluoromethoxy)Benzaldehyde is a high-purity, multi-functional aromatic aldehyde building block. This compound is valued for its unique trifluoromethoxy and bromo substituents, which impart significant electronic and steric properties, making it a critical intermediate in advanced synthesis. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its polarizable structure.
• Polymer & Resin Modifiers: Incorporated into specialty polymers to modify thermal stability, chemical resistance, and optical properties.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating compound libraries for high-throughput screening.

Basic Information

Product Name	3-Bromo-4-(Trifluoromethoxy)Benzaldehyde
CAS No.	85366-66-1
Molecular Formula	C8H4BrF3O2
Molecular Weight	269.02 g/mol
Synonyms	3-Bromo-4-(trifluoromethoxy)benzaldehyde; 4-(Trifluoromethoxy)-3-bromobenzaldehyde; 3-Bromo-α,α,α-trifluoro-p-anisaldehyde; Benzaldehyde, 3-bromo-4-(trifluoromethoxy)-; 85366-66-1; 3-Bromo-4-trifluoromethoxybenzaldehyde
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-(Trifluoromethoxy)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (nitrogen or argon). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.