Description

1-(2-Chloroethyl)-4-(Trifluoromethyl)Benzene is a versatile and high-value halogenated aromatic building block. This compound is critical for advanced organic synthesis, particularly in the development of complex molecules for the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists in fine chemical and active pharmaceutical ingredient (API) manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing trifluoromethyl and chloroethyl pharmacophores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its unique halogenated structure.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for specialty chemicals used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex biaryl systems.
• Fluorine Chemistry Research: Essential for studying the effects of the trifluoromethyl group on molecular properties and reactivity in academic and industrial R&D.
• Custom Synthesis & Contract Manufacturing: Supplied to custom synthesis facilities for the production of proprietary compounds and novel chemical entities.

Basic Information

Product Name	1-(2-Chloroethyl)-4-(Trifluoromethyl)Benzene
CAS No.	85289-89-0
Molecular Formula	C9H8ClF3
Molecular Weight	208.61 g/mol
Synonyms	2-Chloro-1-[4-(trifluoromethyl)phenyl]ethane; 4-(Trifluoromethyl)phenethyl Chloride; 1-Chloro-2-[4-(trifluoromethyl)phenyl]ethane; α-Chloro-4-(trifluoromethyl)toluene; 2-(4-Trifluoromethylphenyl)ethyl Chloride; (4-Trifluoromethylphenyl)ethyl Chloride; p-(Trifluoromethyl)phenethyl Chloride
EINECS	Contact for details

Quality Control

Our 1-(2-Chloroethyl)-4-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.