Description

15(S)-15-Methyl Prostaglandin D2 is a synthetic analog of the naturally occurring prostaglandin D2, featuring a methyl group at the 15-position. This structural modification enhances its metabolic stability and biological activity, making it a valuable tool for biochemical and pharmacological research. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies investigating inflammation, allergy, and sleep-wake regulation pathways.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies targeting the DP1 and CRTH2 receptors to understand their role in allergic responses and inflammation.
• Biochemical Assay Development: Serves as a critical ligand in competitive binding assays and enzyme inhibition studies to screen for novel therapeutic compounds.
• Cell Signaling Studies: Applied in vitro to investigate the downstream effects of prostaglandin signaling on cellular functions such as proliferation, differentiation, and apoptosis.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control of related pharmaceutical products using techniques like HPLC and LC-MS.
• Preclinical Development: Used in animal model studies to evaluate the efficacy and mechanism of action of drugs targeting the prostaglandin pathway.

Basic Information

Product Name	15(S)-15-Methyl Prostaglandin D2
CAS No.	85280-90-6
Molecular Formula	C22H36O5
Molecular Weight	380.52 g/mol
Synonyms	15(R/S)-15-Methyl Prostaglandin D2; 15-Methyl-PGD2; 11,15-Dihydroxy-9-oxo-15-methylprosta-5,13-dien-1-oic acid; 15-Methylprostaglandin D2; U-46619 (related thromboxane analog, often searched alongside); 15-Me-PGD2; 15(S)-Me-PGD2; 15-Methyl PGD2
EINECS	Contact for details

Quality Control

Every batch of 15(S)-15-Methyl Prostaglandin D2 is manufactured under strict quality management systems. We provide comprehensive analytical documentation to support your research and regulatory needs. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data (HPLC purity, identity confirmation by IR/MS) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is hygroscopic and should be kept in a dry environment. Allow the vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.