Description

Pseudomonic Acid D is a specific stereoisomer of the pseudomonic acid family, a class of compounds known for their potent antibacterial properties. This high-purity intermediate is critical for research and development in novel antibiotic synthesis and targeted therapeutic applications. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology firms, and academic institutions focused on antimicrobial discovery and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel antibiotic agents, particularly those targeting bacterial protein synthesis.
• Antimicrobial Research: Used as a reference standard or active component in studies investigating new mechanisms of action against Gram-positive bacteria, including Staphylococcus aureus.
• Medicinal Chemistry: Serves as a core structure for the development and optimization of new pseudomonic acid derivatives with improved efficacy or pharmacokinetic profiles.
• Biochemical Assays: Employed in in vitro enzymatic assays to study the inhibition of bacterial isoleucyl-tRNA synthetase.
• Analytical Standard: Used as a high-purity calibrant in HPLC, LC-MS, or NMR for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Pseudomonic Acid D
CAS No.	85248-93-7
Molecular Formula	C26H44O9
Molecular Weight	500.63 g/mol
Synonyms	Mupirocin D; (E)-2-Methylbut-2-enoic acid (2S,3R,4S,5S)-5-[(2S,3S,4R,5S)-5-[(2S,3S,4S)-4-hydroxy-3-methyloxolan-2-yl]-3,4-dihydroxy-4-methyloxolan-2-yl]-3,4-dihydroxy-3-methyloxolan-2-yl ester; Antibiotic B 5050 D; Pseudomonic acid D; 9-Hydroxy-4-methoxy-8-methyl-2-oxo-2H-1-benzopyran-7-yl 3-methylbut-2-enoate (isomer D); Component D of Pseudomonic Acid
EINECS	Contact for details

Quality Control

Our Pseudomonic Acid D is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant cGMP and ISO guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.