Description

2-(4-Fluorophenyl)-5-Methylpyridine is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which combines a fluorinated aromatic ring with a methyl-substituted pyridine, making it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the creation of organic electronic materials, such as charge-transport layers or emissive materials for OLEDs, due to its electron-deficient pyridine core.
• Chemical Biology Probe: Utilized as a building block for fluorescent tags or molecular probes to study biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	2-(4-Fluorophenyl)-5-Methylpyridine
CAS No.	85237-65-6
Molecular Formula	C12H10FN
Molecular Weight	187.21 g/mol
Synonyms	5-Methyl-2-(4-fluorophenyl)pyridine; 2-(p-Fluorophenyl)-5-methylpyridine; 4-Fluoro-5'-methyl-2,3'-bipyridine (alternative numbering); 85237-65-6; 2-(4-Fluorophenyl)-5-picoline
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)-5-Methylpyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.