Description

(5Z,13E,15S)-9α,15-Dihydroxy-16,16-Dimethyl-11-Oxoprosta-5,13-Dien-1-Oic Acid is a high-purity synthetic prostaglandin analog, a critical intermediate in advanced pharmaceutical research and development. This compound is valued for its precise stereochemistry and biological activity, enabling the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies focused on developing treatments for inflammatory and cardiovascular conditions.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel prostaglandin-based drugs targeting inflammation, glaucoma, and cardiovascular diseases.
• Biochemical Research: Used as a reference standard and active probe in studies of prostaglandin receptors, signal transduction pathways, and enzyme interactions.
• Drug Discovery Programs: Serves as a core scaffold for medicinal chemistry efforts aimed at creating new chemical entities with optimized potency and selectivity.
• Analytical Standard: Employed in HPLC, LC-MS, and NMR for method development, validation, and quality control of related pharmaceutical products.

Basic Information

Product Name	(5Z,13E,15S)-9α,15-Dihydroxy-16,16-Dimethyl-11-Oxoprosta-5,13-Dien-1-Oic Acid
CAS No.	85235-22-9
Molecular Formula	C22H34O6
Molecular Weight	394.50 g/mol
Synonyms	9α,15-Dihydroxy-16,16-dimethyl-11-oxoprosta-5,13-dien-1-oic Acid; 16,16-Dimethyl-PGE2; 16,16-Dimethylprostaglandin E2; 11-Deoxy-16,16-dimethyl PGE2; 9,15-Dihydroxy-16,16-dimethyl-11-oxo-5-cis,13-trans-prostadienoic Acid; DM-PGE2; 16,16-Dimethyl Prostaglandin E2
EINECS	Contact for details

Quality Control

Our (5Z,13E,15S)-9α,15-Dihydroxy-16,16-Dimethyl-11-Oxoprosta-5,13-Dien-1-Oic Acid is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP standards where required for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.