Description

2,4-Dibromo-6-Fluorotoluene is a halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine atoms on the toluene backbone, which allows for selective functionalization and the introduction of complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine and bromine atoms can enhance compound efficacy and environmental profile.
• Liquid Crystal & OLED Material Production: Acts as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Employed in the creation of specialty polymers and functional materials with unique thermal or optical properties.
• Cross-Coupling Reactions: The bromine atoms make it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, enabling rapid diversification.
• Fluorine Chemistry Research: A valuable reagent for studying the effects of fluorine substitution on aromatic systems in medicinal and materials chemistry.

Basic Information

Product Name	2,4-Dibromo-6-Fluorotoluene
CAS No.	85233-17-6
Molecular Formula	C7H5Br2F
Molecular Weight	267.92 g/mol
Synonyms	1,3-Dibromo-5-fluoro-2-methylbenzene; 2-Methyl-1,3-dibromo-5-fluorobenzene; 6-Fluoro-2,4-dibromotoluene; Toluene, 2,4-dibromo-6-fluoro-; 2,4-Dibromo-6-fluoro-1-methylbenzene; 5-Fluoro-2,4-dibromotoluene
EINECS	Contact for details

Quality Control

Our 2,4-Dibromo-6-Fluorotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent composition. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.