Description

K-Ras-In-1 is a potent and selective small molecule inhibitor targeting the K-Ras oncoprotein, a key driver in various cancers. This high-purity research chemical is essential for advancing oncology and molecular biology studies, particularly in the development of targeted cancer therapies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on signal transduction pathways and precision medicine.

Application

• Oncology Research: Used as a critical tool compound for studying K-Ras signaling pathways and validating drug targets in cancer cell lines and animal models.
• Drug Discovery & Development: Serves as a reference standard and a lead compound in high-throughput screening (HTS) campaigns for novel anti-cancer agents.
• Biochemical Assays: Employed in enzymatic inhibition studies to determine IC50 values and elucidate the mechanism of action against mutant K-Ras proteins.
• Preclinical Studies: Facilitates in vitro and in vivo efficacy testing to evaluate tumor growth inhibition and potential therapeutic windows.
• Academic Research: Supports fundamental research into Ras protein biology, GTPase activity, and downstream effector interactions.
• Biomarker Development: Aids in correlating K-Ras inhibition with cellular responses, contributing to companion diagnostic research.

Basic Information

Product Name	K-Ras-In-1
CAS No.	84783-01-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	K-Ras Inhibitor 1; KRAS-IN-1; K-Ras-In-1; 84783-01-7; K-Ras Oncoprotein Inhibitor; KRAS signaling inhibitor; K-Ras targeted compound
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of K-Ras-In-1 is characterized using advanced analytical techniques to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.