Description

Oxythiamine Hexyl Disulfide is a synthetic derivative of thiamine (vitamin B1) featuring a hexyl disulfide moiety. This structural modification is of significant interest in biochemical research for studying thiamine-dependent enzymes and metabolic pathways. It serves as a valuable analytical standard and research chemical for investigating thiamine antagonism, enzyme inhibition, and potential therapeutic applications. Key industries that utilize this compound include pharmaceutical R&D, academic research institutions, and specialty chemical synthesis.

Application

• Biochemical Research: Used as a potent antagonist and inhibitor in studies of thiamine-dependent enzymes such as transketolase and pyruvate dehydrogenase.
• Metabolic Pathway Analysis: A critical tool for investigating thiamine metabolism, deficiency models, and related disorders in cellular and animal studies.
• Pharmaceutical Development: Serves as a reference standard and intermediate in the research of novel therapeutic agents targeting metabolic diseases.
• Analytical Chemistry: Employed as a high-purity certified reference material (CRM) for method development and quality control in HPLC, LC-MS, and NMR analysis.
• Enzyme Kinetics: Utilized to study enzyme mechanism and inhibition kinetics, providing insights into cofactor binding sites.
• Nutritional Science Research: Applied in studies exploring the molecular basis of thiamine function and the effects of its analogs.

Basic Information

Product Name	Oxythiamine Hexyl Disulfide
CAS No.	84714-58-9
Molecular Formula	C19H30N4O3S2
Molecular Weight	426.60 g/mol
Synonyms	Oxythiamine Hexyl Disulfide; O-Butyrylthiamine Hexyl Disulfide; Thiamine Antagonist; 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-{[hexyl(dithio)]ethyl}-4-methyl-5-thiazolium) chloride; Vitamin B1 Antagonist; Transketolase Inhibitor; Pyruvate Dehydrogenase Inhibitor
EINECS	Contact for details

Quality Control

Our Oxythiamine Hexyl Disulfide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.