Description

n-Acetyl-S-(2-Hydroxyethyl)-L-Cysteine Sodium Salt is a chemically modified derivative of the amino acid cysteine, designed for enhanced stability and solubility. This compound is a critical analytical standard and reagent, primarily used for the detection and quantification of acrylamide and other reactive electrophiles in complex matrices. It serves as an essential tool for quality control and safety testing in the food processing, environmental monitoring, and pharmaceutical research industries.

Application

• Acrylamide Analysis: Acts as a derivatization agent and internal standard for the precise quantification of acrylamide in foodstuffs (e.g., potato chips, coffee, baked goods) via GC-MS or LC-MS/MS.
• Biomarker Research: Used in the study of mercapturic acid pathways to investigate human exposure to toxicants and carcinogens, such as ethylene oxide and acrylonitrile.
• Pharmaceutical Impurity Profiling: Employed in method development and validation for detecting reactive impurities and degradants in drug substances and products.
• Environmental Monitoring: Serves as a reference standard for analyzing water and air samples for contamination by reactive industrial chemicals.
• Clinical Toxicology: Utilized in assays to measure specific mercapturic acid conjugates as biomarkers of metabolic detoxification in biological fluids.
• Method Development & Validation: A key certified reference material (CRM) for establishing and calibrating analytical methods in accredited laboratories.

Basic Information

Product Name	n-Acetyl-S-(2-Hydroxyethyl)-L-Cysteine Sodium Salt
CAS No.	84608-41-3
Molecular Formula	C7H12NNaO4S
Molecular Weight	229.23 g/mol
Synonyms	N-Acetyl-S-(2-hydroxyethyl)-L-cysteine sodium salt; N-Acetyl-S-(2-hydroxyethyl)cysteine sodium salt; 2-[(Acetyl-L-cysteinyl)oxy]ethanol sodium salt; N-Acetyl-3-(2-hydroxyethylthio)alanine sodium salt; AAMA sodium salt; N-Acetyl-S-(2-hydroxyethyl)mercapturic acid sodium salt; Sodium N-acetyl-S-(2-hydroxyethyl)-L-cysteinate; N-Acetyl-S-(2-hydroxyethyl)-DL-cysteine sodium salt (racemic mixture)
EINECS	Contact for details

Quality Control

Our n-Acetyl-S-(2-Hydroxyethyl)-L-Cysteine Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with the high standards required for analytical reference materials and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.