Description

Chloro-Sibutramine Hcl CAS NO 84485-08-5 is a synthetic chemical compound of significant interest in advanced pharmaceutical research and development. This substance serves as a key intermediate or reference standard for the synthesis and analytical study of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in metabolic and central nervous system (CNS) drug discovery programs.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in drug testing laboratories.
• Chemical Intermediate: Serves as a critical building block in the multi-step synthesis of complex organic molecules for pharmacological screening.
• Metabolic Research: Employed in in vitro and preclinical studies investigating metabolic pathways and enzyme interactions.
• Analytical Chemistry: Utilized for calibrating equipment such as HPLC, LC-MS, and NMR spectrometers to ensure accurate compound identification and quantification.
• Academic & Institutional Research: Provides a characterized compound for university and institutional research projects in medicinal chemistry and pharmacology.
• Process Development & Scale-up: Acts as a model compound for optimizing synthetic routes, purification processes, and crystallization studies during pharmaceutical process development.

Basic Information

Product Name	Chloro-Sibutramine Hcl
CAS No.	84485-08-5
Molecular Formula	C17H27Cl2N • HCl
Molecular Weight	366.77 g/mol
Synonyms	1-(4-Chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)cyclobutanemethanamine hydrochloride; Chlorosibutramine hydrochloride; 4-Chlorosibutramine HCl; N-{1-[1-(4-Chlorophenyl)cyclobutyl]-3-methylbutyl}-N,N-dimethylamine hydrochloride; Sibutramine chlorinated analog HCl; Reductil chlorinated derivative
EINECS	Contact for details

Quality Control

Our Chloro-Sibutramine Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced chromatographic and spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.