Description

Deriglidole is a selective and potent antagonist of the I2-imidazoline receptor, a key target in neuropharmacological research. This compound is valued for its high specificity, making it an essential tool for investigating central nervous system pathways related to depression, anxiety, and neuropathic pain. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and contract research organizations (CROs) engaged in preclinical neuroscience studies and drug discovery programs.

Application

• Neuroscience Research: A critical reference standard for studying the role of I2-imidazoline receptors in mood disorders and pain modulation.
• Pharmacological Assay Development: Used as a control compound in high-throughput screening (HTS) to identify novel receptor ligands.
• Drug Discovery & Development: Serves as a lead compound or molecular probe in the design of new central nervous system (CNS) therapeutics.
• Biochemical Mechanism Studies: Employed in in vitro and ex vivo experiments to elucidate receptor binding kinetics and downstream signaling pathways.
• Academic & Clinical Research: Supports fundamental research into imidazoline receptor physiology and its implications for various neurological conditions.

Basic Information

Product Name	Deriglidole
CAS No.	122830-14-2
Molecular Formula	C₁₉H₂₀N₂O
Molecular Weight	292.38 g/mol
Synonyms	Deriglidole; LSL 60101; 2-(2-Benzofuranyl)-2-imidazoline; 2-(1-Benzofuran-2-yl)-4,5-dihydro-1H-imidazole; (RS)-2-(2-Benzofuranyl)-2-imidazoline; LSL-60101; 2-(Benzofuran-2-yl)-4,5-dihydro-1H-imidazole
EINECS	Contact for details

Quality Control

Every batch of Deriglidole is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for purity, related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.