Description

Rimonabant is a selective cannabinoid receptor type 1 (CB1) antagonist, a compound of significant interest in pharmacological research. Its primary value lies in its well-characterized mechanism of action, making it a critical reference standard and a key intermediate in the development of novel therapeutic agents. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on metabolic disorders, addiction, and neurological research. Rimonabant CAS NO 168273-06-1 is supplied to meet the stringent demands of laboratory analysis and advanced chemical synthesis.

Application

• Pharmacological Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical testing.
• Biochemical Research: Serves as a critical tool compound for in vitro and in vivo studies targeting the endocannabinoid system and CB1 receptor pathways.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed as a high-purity building block in the synthesis of novel cannabinoid receptor modulators and related pharmaceutical candidates.
• Metabolic Disorder Research: Utilized in preclinical research investigating potential therapies for obesity, diabetes, and associated metabolic syndromes.
• Neuroscience & Addiction Studies: Applied in research models exploring neurological conditions, substance abuse, and reward system mechanisms.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in medicinal chemistry and molecular pharmacology.

Basic Information

Product Name	Rimonabant
CAS No.	168273-06-1
Molecular Formula	C22H21Cl3N4O
Molecular Weight	463.79 g/mol
Synonyms	SR141716; SR141716A; SR 141716; Acomplia; 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide; N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
EINECS	Contact for details

Quality Control

Our Rimonabant is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and identity confirmation (IR, MS). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Loss on Drying	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.