Description

Orlistat is a potent and specific inhibitor of gastrointestinal lipases, primarily used as an active pharmaceutical ingredient (API). This compound is crucial for the formulation of anti-obesity medications, where it functions by preventing the absorption of dietary fats. It is essential for pharmaceutical manufacturers, research institutions, and developers of weight management solutions requiring a high-purity, reliable API. Our supply of Orlistat CAS NO 96829-58-2 ensures consistent quality and compliance with stringent global pharmaceutical standards.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription and over-the-counter anti-obesity drugs (e.g., Xenical®, Alli®).
• Clinical Research: Utilized in metabolic disorder studies, lipid absorption research, and new therapeutic development.
• Formulation Development: Serves as a key component in the R&D of solid dosage forms like tablets and capsules.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation.
• Veterinary Medicine: Potential application in weight management formulations for companion animals.
• Nutraceutical Blends: Incorporated into advanced dietary supplement formulations targeting fat absorption.

Basic Information

Product Name	Orlistat
CAS No.	96829-58-2
Molecular Formula	C29H53NO5
Molecular Weight	495.74 g/mol
Synonyms	Tetrahydrolipstatin; THL; (S)-2-Formylamino-4-methyl-pentanoic acid (S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester; N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester; Xenical®; Alli®; Orlipastat; Lipase Inhibitor
EINECS	Contact for details

Quality Control

Our Orlistat is manufactured and tested under strict quality systems. We provide material that meets or exceeds relevant pharmacopeial standards, including USP and EP monographs where applicable. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment ensures the API is suitable for GMP manufacturing and global regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) to prevent oxidation. The recommended long-term storage temperature is between 2°C and 8°C (refrigerated). For short-term handling, the product can be kept at controlled room temperature (15-25°C). The container must be kept dry and in a well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%
Specific Rotation	[α]20/D: -28° to -32° (c=1 in CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.