Description

1-(5-Isoquinolinylsulfonyl)-3-Methyl-Piperazine is a specialized heterocyclic sulfonamide compound of significant interest in advanced chemical synthesis. This molecule serves as a critical building block and key intermediate for the development of novel pharmacologically active agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted small molecule libraries and potential therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly those targeting enzyme inhibition.
• Biochemical Research: Used as a tool compound or a starting material in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: The isoquinoline sulfonamide core structure is associated with activity in modulating kinase signaling pathways, making it valuable for oncology and neuroscience research.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce specific functional groups and molecular complexity.
• Academic Research: Utilized in university and institutional labs for chemical methodology development and exploring new reactions of sulfonamide derivatives.

Basic Information

Product Name	1-(5-Isoquinolinylsulfonyl)-3-Methyl-Piperazine
CAS No.	84477-73-6
Molecular Formula	C14H17N3O2S
Molecular Weight	291.37 g/mol
Synonyms	3-Methyl-1-(5-isoquinolinylsulfonyl)piperazine; 1-(Isoquinolin-5-ylsulfonyl)-3-methylpiperazine; 3-Methyl-1-(isoquinoline-5-sulfonyl)piperazine; H-89 (related analog); Isoquinoline-5-sulfonyl-3-methylpiperazine; 5-(3-Methylpiperazin-1-ylsulfonyl)isoquinoline
EINECS	Contact for details

Quality Control

Our production of 1-(5-Isoquinolinylsulfonyl)-3-Methyl-Piperazine adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized and released with a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide materials suitable for research and non-GMP development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.