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Heptakis-(2,6-Di-o-Tert.-Butyldimethylsilyl)-β-Cyclodextrin CAS NO 84346-53-2


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CAS No.:84346-53-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Heptakis-(2,6-Di-o-Tert.-Butyldimethylsilyl)-β-Cyclodextrin is a highly functionalized, silylated derivative of β-cyclodextrin, designed to enhance solubility and provide steric protection for the host molecule. This compound is critical for advanced research and development in supramolecular chemistry, where it acts as a sophisticated host for complex molecular recognition and separation processes. It is primarily utilized by pharmaceutical researchers, analytical chemists, and material scientists working on chiral separation, catalyst design, and drug delivery systems.

Application

  • Chiral Stationary Phases (CSPs): A key component in high-performance liquid chromatography (HPLC) and gas chromatography (GC) columns for the enantiomeric separation of complex pharmaceutical intermediates and fine chemicals.
  • Supramolecular Catalyst Design: Serves as a sterically demanding, hydrophobic scaffold for constructing selective catalysts and enzyme mimics in organic synthesis.
  • Molecular Encapsulation & Drug Delivery: Used to study and improve the solubility, stability, and controlled release of poorly soluble active pharmaceutical ingredients (APIs).
  • Chemical Sensor Development: Employed as a selective receptor layer in sensor technologies for detecting specific organic molecules or ions.
  • Advanced Material Science: Acts as a building block for creating functionalized surfaces, polymers, and nano-structured materials with tailored properties.
  • Reference Standard & Analytical Research: Provides a high-purity standard for method development and validation in analytical laboratories.

Basic Information

Product Name Heptakis-(2,6-Di-o-Tert.-Butyldimethylsilyl)-β-Cyclodextrin
CAS No. 84346-53-2
Molecular Formula C119H252O35Si14
Molecular Weight ~2730.0 g/mol
Synonyms 2,6-Di-O-tert-butyldimethylsilyl-β-cyclodextrin; Heptakis(2,6-di-O-tert-butyldimethylsilyl)-β-cyclodextrin; 2,6-di-O-TBDMS-β-CD; β-Cyclodextrin, 2,6-di-O-(tert-butyldimethylsilyl); TBDMS-β-CD; Per(2,6-di-O-tert-butyldimethylsilyl)-β-cyclodextrin; Heptakis(2,6-di-O-TBDMS)-β-cyclodextrin
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Quality Control

Our Heptakis-(2,6-Di-o-Tert.-Butyldimethylsilyl)-β-Cyclodextrin is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific research-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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