Description

Streptococcal Polysaccharide Ia Group B is a highly purified, type-specific capsular polysaccharide antigen derived from *Streptococcus agalactiae* (Group B Streptococcus, GBS). This compound is of critical importance for the research, development, and production of diagnostic reagents and conjugate vaccines targeting GBS infections. It is essential for laboratories and manufacturers focused on immunology, microbiology, and vaccine development, providing a key reagent for serotyping, immunological studies, and quality control of prophylactic solutions.

Application

• Vaccine Development: As a critical antigenic component in the research and formulation of conjugate vaccines against Group B Streptococcus.
• Diagnostic Reagents: Used as a coating antigen or standard in immunoassays (e.g., ELISA, latex agglutination) for the detection and serotyping of GBS antibodies.
• Immunological Research: Serves as a key tool for studying host immune responses, antibody specificity, and the pathogenesis of streptococcal infections.
• Quality Control & Standardization: Acts as a reference standard for the quality assurance and potency testing of commercial antisera and diagnostic kits.
• Biochemical Studies: Employed in structural analysis, carbohydrate chemistry research, and the investigation of polysaccharide-protein conjugation techniques.

Basic Information

Product Name	Streptococcal Polysaccharide Ia Group B
CAS No.	84280-28-4
Molecular Formula	(C6H10O5)n
Molecular Weight	High molecular weight polymer
Synonyms	Group B Streptococcus Polysaccharide Type Ia; GBS Polysaccharide Ia; Streptococcus agalactiae Capsular Polysaccharide Type Ia; Streptococcal Group B Type Ia Antigen; GBS Ia PS; CPS Ia (GBS)
EINECS	Contact for details

Quality Control

Our Streptococcal Polysaccharide Ia Group B is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for research and in-vitro diagnostic use. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assessment, and specific antigenicity evaluation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC/GPC)	≥ 95% (by polysaccharide content)
Protein Content	≤ 1.0% (w/w)
Nucleic Acid Content	≤ 1.0% (w/w)
Endotoxin	< 10 EU/mg (LAL test)
Moisture Content (KF)	≤ 5.0%
Antigenic Activity	Confirmed by serological assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.