Description

2,2,5,5-Tetramethyl-4-Phenacetyliden Imidazolidine-1-Oxyl Free Radical is a stable nitroxide radical, a key member of the TEMPO-derivative family, with the CAS registry number 84271-26-1. This compound is valued for its role as a highly effective and selective mediator in controlled oxidation reactions and as a spin label in spectroscopic studies. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, polymer, and advanced materials sectors. Its unique structure provides exceptional stability, making it a versatile tool for both synthetic chemistry and analytical applications.

Application

• Polymer Chemistry: As a mediator or control agent in nitroxide-mediated radical polymerization (NMP) for producing polymers with controlled molecular weight and architecture.
• Organic Synthesis: As a catalyst or co-catalyst in the selective oxidation of primary and secondary alcohols to aldehydes and ketones under mild conditions.
• Biochemistry & Biophysics: As a spin probe or spin label in Electron Paramagnetic Resonance (EPR) spectroscopy for studying protein dynamics, membrane fluidity, and macromolecular structure.
• Materials Science: In the surface functionalization of nanoparticles and the development of advanced organic electronic materials.
• Antioxidant Research: As a model compound for studying radical scavenging activity and oxidative stress mechanisms.
• Analytical Chemistry: As a standard or reference material in EPR spectrometry and other analytical techniques.

Basic Information

Product Name	2,2,5,5-Tetramethyl-4-Phenacetyliden Imidazolidine-1-Oxyl Free Radical
CAS No.	84271-26-1
Molecular Formula	C₁₇H₂₃N₂O₂
Molecular Weight	287.38 g/mol
Synonyms	4-Phenacylidene-2,2,5,5-tetramethyl-3-imidazoline-1-oxyl; 4-Phenacylidene-2,2,5,5-tetramethyl-δ³-imidazoline-1-oxyl; 4-Phenacylidene-TEMPO; Phenacylidene-TEMPO; 84271-26-1; 2,2,5,5-Tetramethyl-4-phenacylidene-3-imidazoline-1-oxyl; 4-(2-Oxo-2-phenylethylidene)-2,2,5,5-tetramethyl-3-imidazoline-1-oxyl
EINECS	Contact for details

Quality Control

Every batch of our 2,2,5,5-Tetramethyl-4-Phenacetyliden Imidazolidine-1-Oxyl Free Radical is produced and tested under strict quality management protocols to ensure high purity and consistent performance. We employ advanced analytical techniques including HPLC, NMR, and EPR to verify identity, purity, and radical content. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame. The container must be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Identification (EPR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Radical Content (EPR)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.