Description

16-Aminoprostaglandin F2Alpha Methyl Ester is a chemically modified prostaglandin analog, specifically an amino-substituted derivative of PGF2α. This compound is a critical synthetic intermediate in advanced pharmaceutical research, enabling the development of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of prostaglandin-based drugs, particularly for applications in ophthalmology and reproductive medicine.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel prostaglandin receptor agonists and antagonists.
• Ophthalmic Drug Research: Used in the development of next-generation treatments for glaucoma and ocular hypertension.
• Reproductive Health Research: Serves as a precursor in studies related to fertility control and labor induction.
• Biochemical Probe: Employed in mechanistic studies to understand the role of prostaglandin pathways in cellular signaling and inflammation.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.
• Medicinal Chemistry: Facilitates structure-activity relationship (SAR) studies to optimize drug potency and selectivity.

Basic Information

Product Name	16-Aminoprostaglandin F2Alpha Methyl Ester
CAS No.	84121-11-9
Molecular Formula	C22H39NO5
Molecular Weight	397.55 g/mol
Synonyms	16-Amino-PGF2α methyl ester; Methyl (5Z,9α,11α,13E,15S)-9,11,15-trihydroxy-16-aminoprosta-5,13-dien-1-oate; 16-Amino-PGF2α-Me; 16-Aminoprostaglandin F2α methyl ester; Prostaglandin F2α 16-amino methyl ester; 16-Amino-PGF2α methyl ester (CAS 84121-11-9); 16-Amino prostaglandin F2α methyl ester
EINECS	Contact for details

Quality Control

Our 16-Aminoprostaglandin F2Alpha Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and related substances. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store the product at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The container should be kept in a dry, cool, and well-ventilated area. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.