Description

7-Tosyl-7-Desacetylforskolin is a chemically modified derivative of the natural diterpene forskolin, specifically designed for enhanced stability and targeted research applications. This compound is a valuable tool in biochemical and pharmacological research, particularly for studying adenylate cyclase (AC) and cyclic AMP (cAMP) signaling pathways. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors for drug discovery and mechanism-of-action studies.

Application

• Biochemical Research: Used as a potent and selective activator of adenylate cyclase for investigating cAMP-mediated cellular processes.
• Drug Discovery: Serves as a key intermediate or reference standard in the development of novel therapeutics targeting metabolic and cardiovascular diseases.
• Cell Signaling Studies: Employed to elucidate the role of cAMP in cellular functions such as gene expression, ion channel regulation, and hormone secretion.
• Pharmaceutical Reference Standard: Used for quality control, method development, and validation in analytical laboratories.
• Academic Research: A critical reagent for university and institutional labs studying molecular pharmacology and signal transduction.

Basic Information

Product Name	7-Tosyl-7-Desacetylforskolin
CAS No.	84010-23-1
Molecular Formula	C28H36O7S
Molecular Weight	516.65 g/mol
Synonyms	7-O-Tosylforskolin; 7-Tosylforskolin; 7-Desacetyl-7-tosylforskolin; 1α,6β,9α-Trihydroxy-8,13-epoxy-labd-14-en-11-one 7-Tosylate; 7-O-(4-Methylbenzenesulfonyl)forskolin; 7-Ts-Forskolin; 7-Tosyl-7-deacetylforskolin
EINECS	Contact for details

Quality Control

Our 7-Tosyl-7-Desacetylforskolin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.