Description

2-Trifluoromethyl-1H-Quinolin-4-One is a high-value fluorinated heterocyclic building block, essential for advanced organic synthesis. Its core value lies in the trifluoromethyl group, which imparts unique electronic and metabolic properties to target molecules, enhancing their biological activity and physicochemical profile. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and production of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and anti-infective research programs.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and pesticides, leveraging the CF3 group for improved efficacy and environmental stability.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated components.
• Chemical Biology Probe: Employed in the design of molecular probes and fluorescent tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Trifluoromethyl-1H-Quinolin-4-One
CAS No.	83842-55-1
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	4-Hydroxy-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-4-quinolinol; 2-(Trifluoromethyl)quinolin-4(1H)-one; 2-Trifluoromethyl-4-hydroxyquinoline; 4-Quinolinol, 2-(trifluoromethyl)-; 1H-Quinolin-4-one, 2-(trifluoromethyl)-; 83842-55-1
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-1H-Quinolin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, residual solvents, and other critical parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.