Description

1-Naphthyl-B-D-Glucuronide, Sodium Salt is a high-purity biochemical reagent, specifically a glucuronide conjugate of 1-naphthol. This compound is a critical substrate and reference standard in enzymatic assays, particularly for the detection and quantification of β-glucuronidase activity. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic industries requiring precise enzymatic analysis.

Application

• Enzymatic Substrate for β-Glucuronidase: Primary use as a chromogenic or fluorogenic substrate in assays to measure β-glucuronidase enzyme activity in research and clinical diagnostics.
• Diagnostic Reagent Manufacturing: A key raw material in the production of diagnostic kits for detecting bacterial contamination (e.g., E. coli) and certain genetic disorders.
• Biochemical Research: Used in studies of drug metabolism, specifically glucuronidation pathways, and in the development of enzyme-linked immunosorbent assays (ELISAs).
• Pharmaceutical Analysis: Serves as a reference standard in quality control for drug development processes involving prodrug activation or metabolic studies.
• Microbiology: Employed in microbial detection methods where β-glucuronidase is used as a marker for specific bacterial strains.

Basic Information

Product Name	1-Naphthyl-B-D-Glucuronide, Sodium Salt
CAS No.	83833-12-9
Molecular Formula	C₁₆H₁₇NaO₇
Molecular Weight	344.29 g/mol
Synonyms	1-Naphthyl β-D-Glucopyranosiduronic Acid Sodium Salt; Sodium 1-Naphthyl β-D-Glucuronide; β-Glucuronidase Substrate (1-Naphthyl); 1-Naphthol-β-D-glucuronide Sodium Salt; 1-Naphthyl-β-D-glucuronic Acid Sodium Salt; PNPG Sodium Salt; 4-Methylumbelliferyl-β-D-glucuronide (structural analog reference)
EINECS	Contact for details

Quality Control

Our 1-Naphthyl-B-D-Glucuronide, Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.