Description

3-Hydroxy-17-(4-Nitrophenyldithio)-1,3,5(10)-Estratriene is a specialized steroid derivative that serves as a critical intermediate in advanced pharmaceutical research and development. Its unique structure, featuring a nitrophenyldithio moiety, makes it a valuable building block for synthesizing novel therapeutic agents and biochemical probes. This compound is primarily utilized by research institutions and pharmaceutical companies focused on endocrinology, oncology, and the development of targeted molecular therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel steroid-based drugs and hormone analogs for research and development.
• Biochemical Research: Used as a molecular probe or a tagged compound in studies of steroid receptor binding and signal transduction pathways.
• Medicinal Chemistry: Serves as a scaffold for the design and synthesis of new chemical entities with potential therapeutic applications in cancer and metabolic diseases.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and steroid chemistry.

Basic Information

Product Name	3-Hydroxy-17-(4-Nitrophenyldithio)-1,3,5(10)-Estratriene
CAS No.	83797-05-1
Molecular Formula	C24H23NO3S2
Molecular Weight	437.57 g/mol
Synonyms	17β-[(4-Nitrophenyl)dithio]estra-1,3,5(10)-trien-3-ol; 3-Hydroxy-17-(4-nitrophenyldithio)estra-1,3,5(10)-triene; Estra-1,3,5(10)-triene-3-ol, 17-[(4-nitrophenyl)dithio]-, (17β)-; 17-(4-Nitrophenyldithio)estratriene-3-ol; 83797-05-1; Nitrophenyldithioestratriene derivative
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-17-(4-Nitrophenyldithio)-1,3,5(10)-Estratriene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our commitment to quality ensures the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to prevent degradation. Keep the container tightly sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.