Description

Hemicholinium 15-Bromo Mustard is a specialized alkylating agent and a potent choline uptake inhibitor. This compound is of significant value in neuroscience and pharmacological research for its ability to selectively interfere with cholinergic neurotransmission. It is primarily utilized by research institutions and pharmaceutical development laboratories investigating neurodegenerative diseases, synaptic function, and as a tool compound for studying the high-affinity choline transporter (CHT).

Application

• Neuroscience Research: As a high-affinity choline uptake (HACU) inhibitor to study cholinergic systems in the brain.
• Pharmacological Tool Compound: For in vitro and in vivo studies targeting the choline transporter to understand its role in synaptic plasticity.
• Neurodegenerative Disease Models: Used in research related to Alzheimer's disease, myasthenia gravis, and other disorders involving cholinergic deficit.
• Biochemical Assay Development: Serves as a reference standard or active agent in assays designed to screen for cholinergic modulators.
• Academic & Pharmaceutical R&D: Fundamental research into the mechanisms of choline metabolism and the development of novel therapeutic agents.

Basic Information

Product Name	Hemicholinium 15-Bromo Mustard
CAS No.	83291-95-6
Molecular Formula	C16H24Br2N2O2
Molecular Weight	444.19 g/mol
Synonyms	HC-3 Mustard; 15-Bromoacetyl-14,15-dihydrohemicholinium-3; Hemicholinium-3 mustard; 2-[(2-Aminoethyl)methylamino]ethyl 4-[(15-bromoacetyl)-14,15-dihydro-7-hydroxy-2,9-dimethyl-6H-dibenz[b,f]azonin-6-yl]but-2-ynoate; Bromoacetylhemicholinium-3; Choline Uptake Inhibitor Mustard
EINECS	Contact for details

Quality Control

Our Hemicholinium 15-Bromo Mustard is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.