Description

Hc Toxin CAS NO 83209-65-8 is a potent cyclic tetrapeptide mycotoxin produced by the plant pathogenic fungus *Cochliobolus carbonum*. This compound is a critical tool in plant pathology research, primarily valued for its specific role as a host-selective toxin that induces susceptibility in certain maize genotypes. It serves as an indispensable biochemical reagent for scientists and researchers studying plant-microbe interactions, fungal pathogenicity, and programmed cell death in plants. Key industries and applications include agricultural biotechnology, academic research, and the development of plant disease resistance strategies.

Application

• Plant Pathology & Phytotoxin Research: Fundamental studies on host-pathogen specificity and the mechanisms of fungal virulence.
• Plant Cell Biology Studies: Investigation of toxin-induced programmed cell death (apoptosis) and cellular susceptibility in maize.
• Biochemical Research Reagent: Used as a selective agent to study histone deacetylase (HDAC) inhibition in plant and eukaryotic systems.
• Agricultural Biotechnology: Aids in the screening and development of disease-resistant crop varieties, particularly in maize.
• Mode of Action Studies: Research on how host-selective toxins disrupt cellular metabolism and structure in susceptible plant tissues.

Basic Information

Product Name	Hc Toxin
CAS No.	83209-65-8
Molecular Formula	C₂₇H₄₃N₅O₇
Molecular Weight	549.66 g/mol
Synonyms	HC-toxin; Host-specific Toxin from Cochliobolus carbonum; Cyclo(D-Pro-L-Ala-D-Ala-L-Aeo); L-Aeo = 2-Amino-9,10-epoxi-8-oxodecanoic acid; Helminthosporium carbonum Toxin; [cyclo(2-Aminooxiran-2-yl-1-oxodecyl-L-alanyl-D-alanyl-D-prolyl)]; 83209-65-8; Hc-Toxin
EINECS	Contact for details

Quality Control

Our Hc Toxin is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay purity, appearance, and moisture content to meet the stringent requirements of the research and biotechnology sectors.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. Due to its hygroscopic (moisture-sensitive) nature, the container must be sealed under an inert atmosphere or with desiccant after each use to maintain stability and prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, ethanol; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.