Description

Acetyl-Acth (2-24) (Human, Bovine, Rat) is a synthetic peptide fragment derived from adrenocorticotropic hormone (ACTH), specifically acetylated at the N-terminus. This modification is crucial for enhancing its stability and biological activity in research applications, making it a valuable tool for studying the melanocortin system and related endocrine pathways. It is primarily utilized by researchers and pharmaceutical developers in the fields of endocrinology, neuroscience, and drug discovery. The compound is supplied with high purity and batch-to-batch consistency to ensure reliable experimental results.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating ACTH receptor (MC2R) signaling and melanocortin system function.
• Endocrinology Studies: Essential for in vitro and in vivo research on adrenal cortex stimulation, steroidogenesis, and stress response mechanisms.
• Neuroscience Research: Applied in studies exploring the role of melanocortins in behavior, inflammation, and neuroprotection.
• Drug Discovery & Development: Serves as a key pharmacologically active peptide for screening assays, structure-activity relationship (SAR) studies, and the development of novel MC2R agonists or antagonists.
• Biochemical Assay Development: Utilized as a calibrated standard in ELISA, RIA, and other immunoassays designed to detect or quantify ACTH-related peptides.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental scientific investigation into peptide hormone action.

Basic Information

Product Name	Acetyl-Acth (2-24) (Human, Bovine, Rat)
CAS No.	1815617-98-1
Molecular Formula	C136H210N40O39S
Molecular Weight	2933.4 g/mol
Synonyms	Acetyl-ACTH (2-24); N-Acetyl-ACTH (2-24); Acetylated Adrenocorticotropic Hormone (2-24); Ac-ACTH(2-24); Acetyl-ACTH(2-24) amide (human, bovine, rat); Nα-Acetyl-ACTH (2-24); Melanocortin 2 Receptor Ligand; Corticotropin (2-24) acetate (N-acetyl)
EINECS	Contact for details

Quality Control

Every batch of Acetyl-Acth (2-24) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the exacting standards required for research-grade peptides. Certificates of Analysis (COA) detailing purity (by HPLC), peptide content, amino acid analysis, and mass spectrometry (MS) data are provided with each shipment to guarantee traceability and support your compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.