Description

Lactoylpepstatin CAS NO 82867-32-1 is a potent and specific inhibitor of aspartic proteases, including pepsin and cathepsin D. This compound is a critical research tool for studying protease function and developing therapeutic agents for related diseases. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in proteomics, drug discovery, and biochemical pathway analysis.

Application

• Biochemical Research: A key reagent for the selective inhibition of aspartic proteases like pepsin, renin, and cathepsin D in enzymatic assays and mechanistic studies.
• Drug Discovery & Development: Used as a reference standard and lead compound in the design and screening of novel protease inhibitors for therapeutic applications.
• Proteomics & Cell Biology: Employed to investigate the role of specific proteases in cellular processes, including protein degradation, antigen presentation, and apoptosis.
• Academic & Pharmaceutical R&D: Serves as an essential tool in university and industrial laboratories for fundamental research on enzyme kinetics and inhibitor specificity.
• Diagnostic Reagent Development: Potential use in the formulation of diagnostic kits and assays that require controlled protease activity.

Basic Information

Product Name	Lactoylpepstatin
CAS No.	82867-32-1
Molecular Formula	C₃₄H₆₃N₅O₉
Molecular Weight	685.89 g/mol
Synonyms	Pepstatin A Lactone; (3S,4S)-4-Amino-3-hydroxy-6-methylheptanoyl-L-valyl-N-[(2S,3S)-1-[(2S)-2-[(2S)-2-[(2S,3S)-3-hydroxy-4-methyl-1-oxopentan-2-yl]amino]-3-methylbutanoyl]pyrrolidin-2-yl]-3-methyl-1-oxobutan-2-amide; Isovaleryl-L-valyl-L-valyl-4-amino-3-hydroxy-6-methylheptanoyl-L-alanyl-4-amino-3-hydroxy-6-methylheptanoic acid lactone; Aspartic Protease Inhibitor I; Statine-containing Pepstatin Analog
EINECS	Contact for details

Quality Control

Our Lactoylpepstatin is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency for research applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.