Description

Dcpib is a specialized organic compound with the CAS registry number 82749-70-0, recognized for its utility as a potent and selective inhibitor of volume-regulated anion channels (VRACs). This property makes it a critical research tool in cellular physiology and pharmacology. It is primarily sought after by researchers and development scientists in the fields of neuroscience, cardiovascular research, and oncology for investigating cell volume regulation, apoptosis, and related signaling pathways.

Application

• Neuroscience Research: Used to study the role of VRACs in neuronal excitability, ischemic brain injury, and glial cell function.
• Cardiovascular Research: Employed in investigations of cardiac cell volume regulation under stress conditions and its implications for arrhythmias.
• Cancer Biology Studies: Applied as a tool compound to examine the contribution of anion channels to cancer cell proliferation, migration, and apoptosis.
• Cellular Physiology: A key reagent for fundamental research on regulatory volume decrease (RVD) mechanisms in various cell types.
• Drug Discovery: Serves as a reference standard and pharmacological probe in high-throughput screening and target validation for novel therapeutics.
• Academic & Institutional Research: Essential for universities and research institutes conducting advanced studies in ion channel biology.

Basic Information

Product Name	Dcpib
CAS No.	82749-70-0
Molecular Formula	C15H12Cl2N2O2
Molecular Weight	323.18 g/mol
Synonyms	4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-1-oxo-3H-inden-5-yl)oxy]butanoic Acid; DCPIB; VRAC Inhibitor DCPIB; 2-Butyl-6,7-dichloro-5-[(4-oxobutoxy)]-2-cyclopentyl-1-indanone; Volume-Regulated Anion Channel Blocker
EINECS	Contact for details

Quality Control

Our Dcpib is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and structural confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.