Description

5-Fluoro-2-Nitrobenzene-1-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to act as a sulfonylation reagent, introducing the sulfonyl functional group to create novel compounds with specific properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Research & Development: A valuable reagent for constructing complex molecular architectures in medicinal chemistry and material science.
• Dye and Pigment Manufacturing: Serves as an intermediate for producing specialized sulfonated dyes and colorants.
• Polymer Modification: Can be used to introduce sulfonyl groups into polymers to alter their physical or chemical properties.
• Cross-coupling Reactions: Acts as an electrophile in palladium-catalyzed cross-coupling reactions to form carbon-sulfur bonds.

Basic Information

Product Name	5-Fluoro-2-Nitrobenzene-1-Sulfonyl Chloride
CAS No.	82711-97-5
Molecular Formula	C6H3ClFNO4S
Molecular Weight	239.61 g/mol
Synonyms	5-Fluoro-2-nitrobenzenesulfonyl chloride; 2-Nitro-5-fluorobenzenesulfonyl chloride; 1-Fluoro-4-nitro-2-sulfonylchloridebenzene; 82711-97-5; 5-Fluoro-2-nitrobenzene-1-sulfonyl chloride; 5-Fluoro-2-nitrobenzenesulphonyl chloride; 2-Nitro-5-fluorophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Nitrobenzene-1-Sulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.