Description

Benzene, 1-(3-Chloropropyl)-3-(Trifluoromethyl)- is a specialized organic intermediate featuring both a reactive chloropropyl side chain and a stable trifluoromethyl group. This unique bifunctional structure makes it a valuable building block for synthesizing advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the incorporation of a fluorine-containing moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce functional side chains into polymers, altering their surface properties, solubility, or reactivity for specialty coatings and resins.
• Cross-coupling Reactions: The chloropropyl group acts as a handle for further functionalization via palladium-catalyzed or other metal-mediated coupling reactions.
• Fluorine Chemistry Research: A valuable reagent in academic and industrial R&D for exploring new reactions and properties imparted by the CF3 group.

Basic Information

Product Name	Benzene, 1-(3-Chloropropyl)-3-(Trifluoromethyl)-
CAS No.	82258-76-2
Molecular Formula	C10H10ClF3
Molecular Weight	222.64 g/mol
Synonyms	1-(3-Chloropropyl)-3-(trifluoromethyl)benzene; 3-(3-Chloropropyl)benzotrifluoride; m-(3-Chloropropyl)benzotrifluoride; (3-Chloropropyl)(3-trifluoromethyl)benzene; 3-Trifluoromethyl-1-(3-chloropropyl)benzene; α,α,α-Trifluoro-m-(3-chloropropyl)toluene; 1-Chloro-3-(3-trifluoromethylphenyl)propane
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of Benzene, 1-(3-Chloropropyl)-3-(Trifluoromethyl)- is characterized and verified to meet strict purity specifications. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request. Our quality management system supports cGMP and ISO standards for reliable, batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The compound is moisture-sensitive; keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.