Description

Etolotifen CAS NO 82140-22-5 is a synthetic organic compound belonging to the benzothiophene class, recognized for its specific pharmacological activity. This compound is of significant interest in the research and development of novel therapeutic agents, particularly for its potential role in modulating specific biological pathways. It serves as a critical pharmaceutical intermediate and a valuable reference standard for analytical and quality control purposes. Primary users include pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and companies specializing in the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced active pharmaceutical ingredients (APIs) for clinical research.
• Reference Standard: High-purity material used for method development, validation, and quality control (QC) testing in analytical laboratories.
• Biochemical Research: Used in in vitro and in vivo studies to investigate specific receptor interactions and pharmacological effects.
• Process Development: Employed in scaling up synthetic routes and optimizing manufacturing processes for new chemical entities (NCEs).
• Custom Synthesis: Serves as a starting material for the preparation of novel analogs and derivatives in medicinal chemistry programs.

Basic Information

Product Name	Etolotifen
CAS No.	82140-22-5
Molecular Formula	C19H21NOS
Molecular Weight	311.44 g/mol
Synonyms	Etolotifene; 2-(Diethylamino)ethyl 5-methoxy-2-methyl-1-benzothiophene-3-carboxylate; 5-Methoxy-2-methyl-1-benzothiophene-3-carboxylic acid 2-(diethylamino)ethyl ester; 1-Benzothiophene-3-carboxylic acid, 5-methoxy-2-methyl-, 2-(diethylamino)ethyl ester; EINECS 279-914-1; UNII-3V9L3JY9V2
EINECS	279-914-1

Quality Control

Our Etolotifen is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation (IR, NMR). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing the results against agreed specifications. Our quality commitment ensures the material is suitable for its intended use in research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.